Raman spectroscopy - advanced optical analysis technology
Boost plant safety, ensure product quality, and optimize operations. Raman spectroscopy measures the composition and molecular structure of your samples from lab-to-process in real time.
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*Please contact your Endress+Hauser sales partner for any further questions.
Specs at a glance
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Laser wavelength
785 nm, 1000 nm -
Wetted materials
Body: 316L stainless steel
Window: Proprietary material, optimized for bioprocesses
Process connection: PG13.5 for industry standard sensor housings, welded port connectors available
Surface finish: Ra 15 with electropolish
Adhesive: USP Class VI and ISO993 compatible -
Sterilization method
CIP/SIP
Field of application
The Raman Rxn-45 probe capitalizes on the power of Raman in bioprocess manufacturing by measuring multiple, specific components in real-time for continuous, around-the-clock process feedback. It also meets the daunting sampling requirements of compliance, sterilization, port compatibility, and convenience. The Raman Rxn-45 probe was designed for installation in development and cGMP stainless-steel reactors and is successfully used to provide an analytical “eye” into large-scale bioprocesses.
Cell culture: glucose, lactate, amino acids, cell density, titer, and more
Fermentation: glucose, glycerol, acetate, methanol, ethanol, biomass, and more
Benefits
Measures multiple components in real-time for automated 24/7 process feedback
Provides long-term measurement stability
Offers a suitable surface finish for cGMP manufacturing
Provides compatibility with industry standard bioreactor side ports and sensor housings
Offers the flexibility of being installed in development and production reactors
Reduces sterilization and cleaning burdens with CIP/SIP standard compatibility
Extended selection
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High-end products
- Highly functional and convenient
Technical excellence
Simplicity
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Standard products
- Reliable, robust and low-maintenance
Technical excellence
Simplicity
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Specialized products
- Designed for demanding applications
Technical excellence
Simplicity
Variable
| FLEX selections | Technical excellence | Simplicity |
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Fundamental selection Meet your basic measurement needs |
Technical excellence
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Simplicity
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Lean selection Handle your core processes easily |
Technical excellence
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Simplicity
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Extended selection Optimize your processes with innovative technologies |
Technical excellence
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Simplicity
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Xpert selection Master your most challenging applications |
Technical excellence
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Simplicity
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Success stories
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33 documents
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Technical Information (TI)
Rxn-45 Raman spectroscopic probe Technical Information
System design and specifications for the Raman Rxn-45 probe
EN 13/12/2024Language:
English
Version:
13/12/2024
File size:
352.9 KB
File name:
TI01633CEN_0323.pdf
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Operating Instruction (BA)
Rxn-45 Raman spectroscopic probe Operating Instructions
Commissioning, operation, and maintenance details
for the Raman Rxn-45 probeEN 02/12/2024Language:
English
Version:
02/12/2024
File size:
806.9 KB
File name:
BA02169CEN_0323.pdf
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Short Instruction (KA)
Rxn-45 Raman spectroscopic probe Brief Operating Instructions
Quick start guide for the Raman Rxn-45 probe
Language:
English
Version:
02/12/2024
File size:
565.8 KB
File name:
KA01549CEN_0323.pdf
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PU (Publication)
Endress+Hauser - your one-source Life Sciences technology partner
Graphic highlighting why Endress+Hauser is trusted by the
world's top biopharmaceutical manufacturers for its Life
Sciences expertise and reliable inline, real-time measurement
technologies like Raman spectroscopy systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology (Liquiline CM44P, CM442 and
OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E,
CLS82E).Language:
English
Version:
27/06/2024
File size:
1.9 MB
File name:
PU01585CEN_0124.pdf
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PU (Publication)
Raman application guide for the life science industry - Trusted composition analysis for the life sciences
A guide to our Raman spectroscopy application notes for the
Life Science industry (featuring the Raman Rxn2 analyzer,
Raman Rxn4 analyzer, Rxn-10 probe, Rxn-20 probe, Rxn-45 probe,
Rxn-46 probe, and probe accessory optics (bIO-Optic, Raman single
use optic system / SUB, immersion optic, non-contact optic).Language:
English
Version:
19/04/2022
File size:
1.1 MB
File name:
PU01447CEN_0222.pdf
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PU (Publication)
Prioritize scalability for an efficient biopharmaceutical product development lifecycle
This technical paper studies the importance of scalability as a
competitive advantage in bioprocessing in the Life Science industry,
and Endress+Hauser's scalable Raman systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology and Liquid Analysis portfolio
(Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and
Memosens CPS61E, CLS82E, COS81E, CLS82E).Language:
Czech
Version:
06/09/2024
File size:
381.4 KB
File name:
PU01584CEN_0124_cz_view.pdf
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PU (Publication)
Endress+Hauser - ライフサイエンス技術のワンストップパートナー
Endress+Hauserが、ライフサイエンス分野の専門知識と、ラマン分
光システム（Raman Rxn2、Raman Rxn4、Rxn-10、Rxn-45、Rxn-46、
バイオマルチオプティックおよびスリーブ、フローフィル、フロー
ベンチ、シングルユース用Ramanオプティックシステム）や水質分
析センサ技術（Liquiline CM44P、CM442、OUSAF44、OUSBT66、
Memosens CPS61E、CLS82E、COS81E、CLS82E）などの信頼性の高い
インラインおよびリアルタイム測定技術によって、世界トップクラ
スのバイオ医薬品メーカーから信頼されている理由を強調したグラ
フィック。Language:
Japanese
Version:
04/10/2024
File size:
2.7 MB
File name:
PU01585CJA_0124_Graphic_EH biopharma trust.pdf
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PU (Publication)
Advanced process and product control in fermentations - Raman spectroscopy for composition analysis in a lab or process
An overview of Raman spectroscopy analyzer systems (including the
Raman Rxn2 analyzer, Raman Rxn4 analyzer, Rxn-10 probe, and Rxn-45
probe), powered by Kaiser Raman technology, for fermentation
compositional analysis in a lab or process applicable to biotechnology
in the food & beverage industry.Language:
English
Version:
03/03/2022
File size:
603 KB
File name:
PU01457CEN_0122.pdf
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PU (Publication)
ライフサイエンス産業向けのラマンアプリケーションガイド -ライフサイエンスのための信頼できる組成分析
ライフサイエンス産業向けラマン分光法アプリケーションノート（
ラマンRxn2アナライザー、ラマンRxn4アナライザー、Rxn-10プロー
ブ、Rxn-20プローブ、Rxn-45プローブ、Rxn-46プローブ、プローブ
オプティックアクセサリ（bIOオプティック、シングルユース向け
ラマンオプティックシステム/SUB、浸漬オプティック、非接触オプ
ティック）。Language:
Japanese
Version:
02/08/2024
File size:
1.4 MB
File name:
PU01447CJA_0222_Raman_App_Guide_for_LifeScience.pdf
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PU (Publication)
Prioritize scalability for an efficient biopharmaceutical product development lifecycle
This technical paper studies the importance of scalability as a
competitive advantage in bioprocessing in the Life Science industry,
and Endress+Hauser's scalable Raman systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology and Liquid Analysis portfolio
(Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and
Memosens CPS61E, CLS82E, COS81E, CLS82E).Language:
English
Version:
27/06/2024
File size:
753.7 KB
File name:
PU01584CEN_0124.pdf
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